Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACIP00000004036Sorbin and SH3 domain containing 1. (612 aa)    
Predicted Functional Partners:
ENSACIP00000022464
Vinculin a.
   
 0.973
ENSACIP00000031692
Vinculin b.
   
 0.973
ENSACIP00000014942
Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.
    
  0.927
ENSACIP00000017469
Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.
    
  0.927
ENSACIP00000022271
Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.
    
  0.927
ENSACIP00000030377
Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.
    
  0.927
ENSACIP00000003116
Afadin, adherens junction formation factor a.
    
 0.899
ENSACIP00000001549
Vesicle (multivesicular body) trafficking 1.
    
 
 0.837
ENSACIP00000004170
GTP cyclohydrolase 2.
    
   0.777
ENSACIP00000027756
GTP cyclohydrolase 1.
    
   0.777
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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