Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSACIP00000004062S-phase kinase-associated protein 2, E3 ubiquitin protein ligase. (409 aa)    
Predicted Functional Partners:
ENSACIP00000003379
Cullin 1b; Belongs to the cullin family.
    
 0.999
ENSACIP00000017602
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
    
 0.999
ENSACIP00000020012
Retinoblastoma 1.
   
 0.999
ENSACIP00000012470
Ring-box 1, E3 ubiquitin protein ligase.
    
 0.998
ENSACIP00000020764
Chromatin licensing and DNA replication factor 1.
   
 
 0.993
ENSACIP00000020810
E2F transcription factor 1.
    
 0.993
ENSACIP00000002164
Cyclin E2; Belongs to the cyclin family.
   
 0.988
ENSACIP00000011479
Cyclin E1; Belongs to the cyclin family.
   
 0.988
ENSACIP00000005182
Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
   
 0.987
ENSACIP00000017107
Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
   
 0.987
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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