Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACIP00000004073DNA fragmentation factor, alpha polypeptide. (324 aa)    
Predicted Functional Partners:
ENSACIP00000020084
DNA fragmentation factor, beta polypeptide (caspase-activated DNase).
    
 0.901
ENSACIP00000006758
Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family.
    
  0.877
CASP3
Caspase 3; Belongs to the peptidase C14A family.
    
  0.877
CASP3-2
Caspase 3; Belongs to the peptidase C14A family.
    
  0.877
ENSACIP00000018580
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
     
  0.865
ENSACIP00000018811
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
     
  0.865
ENSACIP00000013253
Caspase 7, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
    
  0.845
ENSACIP00000029514
Uncharacterized protein; Belongs to the peptidase C14A family.
    
  0.845
ENSACIP00000001486
Protein kinase, AMP-activated, beta 1 non-catalytic subunit, a.
    
  0.770
PRKAB2
Protein kinase AMP-activated non-catalytic subunit beta 2.
    
  0.770
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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