Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACIP00000004074Uncharacterized protein. (177 aa)    
Predicted Functional Partners:
ENSACIP00000007214
Melanocortin 2 receptor.
    
 0.999
POMC
Proopiomelanocortin.
    
 0.993
ENSACIP00000027983
Spindle and centriole associated protein 1.
   
    0.962
ENSACIP00000006839
Uncharacterized protein.
    
 0.960
ENSACIP00000012852
Melanocortin 2 receptor accessory protein 2b.
    
 
 0.863
ENSACIP00000024880
Melanocortin 4 receptor.
    
 0.851
ENSACIP00000007195
Melanocortin 5b receptor.
    
 0.765
ENSACIP00000005621
Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family.
    
 0.759
ENSACIP00000010858
Ankyrin repeat domain 22.
      
 0.624
DIAPH1
Diaphanous related formin 1.
      
 0.572
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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