Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACIP00000004181Rho guanine nucleotide exchange factor (GEF) 10-like b. (983 aa)    
Predicted Functional Partners:
ENSACIP00000006454
Transmembrane protein 173.
   
 0.882
ENSACIP00000017182
Tumor protein p53 binding protein, 1.
    
 0.800
ENSACIP00000012930
Ubiquitin carboxyl-terminal hydrolase.
      
 0.617
ENSACIP00000022014
Pleckstrin homology domain containing, family G (with RhoGef domain) member 5b.
    
 0.603
AFMID
Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.
   
  
 0.599
ENSACIP00000027868
Uncharacterized protein.
     
  0.577
ENSACIP00000030831
Ketohexokinase.
      
 0.573
CDC42
Cell division cycle 42.
    
 0.570
ENSACIP00000025287
Uncharacterized protein.
    
 0.570
ENSACIP00000014411
Ras homolog family member H.
    
 0.561
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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