Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
ENSACIP00000004253Fork-head domain-containing protein. (300 aa)    
Predicted Functional Partners:
ENSACIP00000002689
Sulfite oxidase.
     
  0.768
ENSACIP00000029034
Serum/glucocorticoid regulated kinase family member 3.
    
 0.661
ENSACIP00000004941
Deacetylase sirtuin-type domain-containing protein.
    
 0.531
SIRT5
NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.
    
 0.531
SIRT5-2
NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.
    
 0.531
ENSACIP00000004883
Uncharacterized protein.
  
 
 0.505
ENSACIP00000030495
Peptidyl-prolyl cis-trans isomerase.
    
  0.501
ENSACIP00000002362
WD repeat domain 73.
    
 0.484
ENSACIP00000020299
Retinoblastoma binding protein 4.
    
 0.484
ENSACIP00000022550
Uncharacterized protein.
    
 0.484
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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