Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACIP00000004288TBC1 domain family, member 17. (642 aa)    
Predicted Functional Partners:
ENSACIP00000025544
Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering.
    
 0.930
ENSACIP00000014179
Si:dkey-13a21.4.
   
 0.916
ENSACIP00000017858
RAB7a, member RAS oncogene family.
    
 0.907
ENSACIP00000028882
Uncharacterized protein.
    
 0.907
ENSACIP00000028893
RAB7A, member RAS oncogene family.
    
 0.905
ENSACIP00000001024
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
    
 0.884
ENSACIP00000025522
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
    
 0.884
ENSACIP00000020294
TBC1 domain family, member 15.
     
  0.865
ENSACIP00000007454
Optineurin.
   
 0.842
ENSACIP00000008610
Armadillo repeat containing 5.
   
 0.822
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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