Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Experiments
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[Homology]
Score
ENSACIP000000042975-hydroxytryptamine (serotonin) receptor 1A a. (412 aa)    
Predicted Functional Partners:
GNG4
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
 0.931
ENSACIP00000012471
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
 0.931
ENSACIP00000000503
Guanine nucleotide binding protein (G protein), beta polypeptide 2.
    
  0.916
ENSACIP00000016438
Guanine nucleotide binding protein (G protein), beta polypeptide 4b.
    
  0.916
ENSACIP00000011695
Guanine nucleotide binding protein (G protein), beta polypeptide 1b.
    
  0.908
ENSACIP00000019837
Guanine nucleotide binding protein (G protein), beta polypeptide 1a.
    
  0.908
ENSACIP00000016618
Guanine nucleotide binding protein (G protein), beta polypeptide 3a.
    
  0.906
ENSACIP00000006716
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.
    
 0.904
ENSACIP00000010014
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b.
    
 0.904
ENSACIP00000027876
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2a.
    
 0.904
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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