Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSACIP00000004359H15 domain-containing protein. (238 aa)    
Predicted Functional Partners:
ENSACIP00000030855
La ribonucleoprotein domain family, member 7.
    
   0.747
ENSACIP00000016361
Actin-like 6A; Belongs to the actin family.
    
 
 0.731
ENSACIP00000010618
Bromodomain adjacent to zinc finger domain, 1B.
   
 0.715
ENSACIP00000003782
Histone H2A; Belongs to the histone H2A family.
   
 
 0.711
H2AZ1
Histone H2A; Belongs to the histone H2A family.
   
 
 0.711
ENSACIP00000005360
NOC2-like nucleolar associated transcriptional repressor.
    
   0.680
ENSACIP00000016779
H2A histone family, member Y; Belongs to the histone H2A family.
   
 0.671
ENSACIP00000011102
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 0.669
H4C13
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 0.669
ENSACIP00000026778
Histone 1, H4, like.
   
 0.669
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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