Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACIP00000004385Uncharacterized protein. (77 aa)    
Predicted Functional Partners:
ENSACIP00000025055
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
   
 
 0.922
ENSACIP00000013147
Cofilin 1; Belongs to the actin-binding proteins ADF family.
   
 
 0.852
ENSACIP00000028180
Cofilin 2 (muscle); Belongs to the actin-binding proteins ADF family.
   
 
 0.852
ENSACIP00000014087
Adenylyl cyclase-associated protein; Belongs to the CAP family.
   
 
 0.839
ENSACIP00000014100
CAP_N domain-containing protein.
   
 
 0.839
ENSACIP00000019414
Adenylyl cyclase-associated protein; Belongs to the CAP family.
   
 
 0.839
ENSACIP00000029594
ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.
   
 
 0.823
ACTA1
Actin alpha 1, skeletal muscle.
   
 0.797
ENSACIP00000010903
Actin alpha 2, smooth muscle.
   
 0.797
ENSACIP00000011505
Uncharacterized protein.
   
 0.797
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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