Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSACIP00000004448Hyperpolarization activated cyclic nucleotide-gated potassium channel 4. (1158 aa)    
Predicted Functional Partners:
ENSACIP00000023969
XK-related protein.
     
  0.695
ENSACIP00000029408
XK-related protein.
     
  0.695
ENSACIP00000001809
Short stature homeobox 2.
    
 
 0.679
ENSACIP00000003133
Uncharacterized protein.
     
  0.598
ENSACIP00000019456
RAB guanine nucleotide exchange factor (GEF) 1, like.
     
  0.598
ENSACIP00000020986
RAB guanine nucleotide exchange factor (GEF) 1.
     
  0.598
ENSACIP00000007298
T-box transcription factor 18.
      
 0.577
ENSACIP00000012949
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
    
 0.576
ENSACIP00000012961
Na_trans_assoc domain-containing protein.
    
 0.576
ENSACIP00000021621
NK2 homeobox 5.
      
 0.553
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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