Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
GUCY1A2Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (801 aa)    
Predicted Functional Partners:
ENSACIP00000027832
Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
  
0.994
ENSACIP00000001525
Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
   
0.992
ENSACIP00000027777
Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
  
  
 
0.937
ENSACIP00000002451
Phosphodiesterase.
   
 0.927
ENSACIP00000004750
Phosphodiesterase 9A; Belongs to the cyclic nucleotide phosphodiesterase family.
   
 0.927
ENSACIP00000023963
Phosphodiesterase.
   
 0.914
ENSACIP00000030444
PDEase domain-containing protein; Belongs to the cyclic nucleotide phosphodiesterase family.
   
 0.914
ENSACIP00000002606
cGMP-dependent protein kinase.
  
 0.905
ENSACIP00000003788
Protein kinase cGMP-dependent 1b.
  
 0.905
ENSACIP00000006444
Si:dkey-121j17.5; Belongs to the protein kinase superfamily.
  
 0.905
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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