Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACIP00000004474Uncharacterized protein. (830 aa)    
Predicted Functional Partners:
COQ3
Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
   
 0.783
ENSACIP00000013923
Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
  
 
 0.706
ENSACIP00000016057
Guanine monophosphate synthase.
    
  0.665
ENSACIP00000019504
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.
    
 0.657
ENSACIP00000026711
Epoxide hydrolase 2, cytoplasmic.
  
 
 0.598
ENSACIP00000013209
HemK methyltransferase family member 1.
    
  0.594
ENSACIP00000021885
N-6 adenine-specific DNA methyltransferase 1.
    
  0.594
ENSACIP00000007208
Sorbitol dehydrogenase.
    
 0.586
ENSACIP00000002939
5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.
    
  0.583
ENSACIP00000013535
Metallophos domain-containing protein.
    
  0.583
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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