Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ENSACIP00000004482Rho guanine nucleotide exchange factor (GEF) 28a. (1178 aa)    
Predicted Functional Partners:
ENSACIP00000023725
Serine/threonine kinase 11; Belongs to the protein kinase superfamily.
     
  0.808
ENSACIP00000002863
Cingulin-like 1.
     
 0.775
ENSACIP00000012318
Guanine nucleotide binding protein (G protein), alpha 13b.
    
 0.766
GNA12
G protein subunit alpha 12.
    
 0.766
ENSACIP00000023260
Guanine nucleotide binding protein (G protein), alpha 13b.
    
 0.766
ENSACIP00000000758
PDZ domain-containing protein.
    
 0.751
ENSACIP00000006767
Uncharacterized protein.
    
 0.751
MPDZ
Multiple PDZ domain crumbs cell polarity complex component.
    
 0.751
ENSACIP00000004929
Cingulin b.
     
  0.749
ENSACIP00000013711
Cingulin a.
     
  0.749
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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