Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ENSACIP00000004680Multiple EGF-like-domains 11. (1043 aa)    
Predicted Functional Partners:
ENSACIP00000003321
GULP PTB domain containing engulfment adaptor 1a.
   
 0.976
ENSACIP00000022135
C1q domain-containing protein.
   
 
  0.861
ENSACIP00000022113
C1q domain-containing protein.
     
  0.860
ENSACIP00000022180
C1q domain-containing protein.
     
  0.860
ENSACIP00000013460
CARD domain-containing protein.
     
  0.705
ENSACIP00000011286
AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]
      
 0.696
ENSACIP00000022834
Tyrosine-protein kinase.
    
 0.668
ENSACIP00000014523
Complement component 8, beta polypeptide.
   
  0.634
AXL
AXL receptor tyrosine kinase.
    
 0.629
ENSACIP00000029070
Uncharacterized protein.
    
  0.620
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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