Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSACIP00000004685PRP39 pre-mRNA processing factor 39 homolog (yeast). (617 aa)    
Predicted Functional Partners:
SNRPC
U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...]
   
 0.939
ENSACIP00000017055
Small nuclear ribonucleoprotein polypeptide F.
    
 0.922
ENSACIP00000027025
Splicing factor 3b, subunit 1.
   
 
 0.917
ENSACIP00000023047
Small nuclear ribonucleoprotein 70 (U1).
    
 0.913
ENSACIP00000002353
tRNA selenocysteine 1 associated protein 1b.
   
 
 0.883
ENSACIP00000005359
tRNA selenocysteine 1 associated protein 1a.
   
 
 0.883
ENSACIP00000000628
LUC7-like (S. cerevisiae).
   
 0.880
ENSACIP00000003052
Zgc:158803.
   
 0.880
ENSACIP00000027512
Small nuclear ribonucleoprotein polypeptide A.
    
 
 0.872
ENSACIP00000025461
N(alpha)-acetyltransferase 38, NatC auxiliary subunit.
    
 
 0.866
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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