Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ENSACIP00000004690SIX homeobox 3b. (277 aa)    
Predicted Functional Partners:
ENSACIP00000019393
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
   
 0.708
ENSACIP00000021845
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
   
 0.708
ENSACIP00000028344
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
   
 0.708
ENSACIP00000029427
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
   
 0.708
VSX2
Visual system homeobox 2.
   
  
 0.556
ENSACIP00000001340
Distal-less homeobox 1a.
   
  
 0.521
ENSACIP00000008641
Orthodenticle homeobox 2b.
    
 
 0.510
ENSACIP00000012861
Ventral anterior homeobox 2.
   
 
 0.509
ENSACIP00000008967
Paired domain-containing protein.
  
  
 0.506
ENSACIP00000004898
Homeobox domain-containing protein.
    
 
 0.490
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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