Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSACIP00000004716Inositol polyphosphate-5-phosphatase F. (1097 aa)    
Predicted Functional Partners:
ENSACIP00000011147
Phosphoinositide phospholipase C.
     
 0.897
ENSACIP00000003719
Myotubularin related protein 6.
     
 0.885
ENSACIP00000014165
Myotubularin related protein 3.
     
 0.880
ENSACIP00000014706
Myotubularin phosphatase domain-containing protein.
     
 0.879
ENSACIP00000027867
Myotubularin related protein 7a.
     
 0.879
ENSACIP00000002584
Inositol polyphosphate-5-phosphatase E.
     
 0.878
ENSACIP00000019015
Myotubularin related protein 1a.
     
 0.878
PLCB4
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
     
 0.876
ENSACIP00000021988
Phosphatidylinositol-4-phosphate 5-kinase, type I, gamma b.
     
 0.876
ENSACIP00000031549
Phosphatidylinositol-4-phosphate 5-kinase, type I, gamma a.
     
 0.876
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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