Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSACIP00000004725Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (351 aa)    
Predicted Functional Partners:
ENSACIP00000006210
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3.
   
 0.964
ENSACIP00000013884
A-Raf proto-oncogene, serine/threonine kinase.
   
 0.964
ENSACIP00000018768
Mitogen-activated protein kinase kinase kinase 8.
    
 0.961
ENSACIP00000007539
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
 0.955
ENSACIP00000008799
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
 0.955
ENSACIP00000004441
Raf-1 proto-oncogene, serine/threonine kinase a.
   
 0.954
ENSACIP00000027229
B-Raf proto-oncogene, serine/threonine kinase.
   
 0.954
ENSACIP00000027344
Mitogen-activated protein kinase kinase kinase 4.
    
 0.952
ENSACIP00000022036
Mitogen-activated protein kinase.
   
 0.944
ENSACIP00000017091
P21 protein (Cdc42/Rac)-activated kinase 2b; Belongs to the protein kinase superfamily.
    
 0.909
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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