Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSACIP00000004763Ubiquitination factor E4B, UFD2 homolog (S. cerevisiae). (1201 aa)    
Predicted Functional Partners:
ENSACIP00000020913
Ubiquitin-like 7b (bone marrow stromal cell-derived).
   
 0.984
ENSACIP00000015436
Thyroid hormone receptor interactor 12.
   
 0.969
ENSACIP00000020373
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 
 0.956
ENSACIP00000018597
Zgc:136908.
  
 
 0.952
ENSACIP00000026468
Valosin containing protein; Belongs to the AAA ATPase family.
  
 
 0.952
ENSACIP00000015026
YOD1 deubiquitinase.
    
 
 0.936
ENSACIP00000008489
Ubiquitin recognition factor in ER associated degradation 1.
    
 
 0.918
ENSACIP00000025600
Ubiquilin 4.
   
 0.918
ENSACIP00000010389
Uncharacterized protein.
    
 0.905
ENSACIP00000002564
Uncharacterized protein.
   
 0.893
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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