Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ENSACIP00000004848Phospholipase D family, member 6. (215 aa)    
Predicted Functional Partners:
ENSACIP00000023996
Fem-1 homolog b (C. elegans).
   
  0.836
ENSACIP00000017021
Phospholipase A2.
     
 0.810
ENSACIP00000016154
Ubiquitin-conjugating enzyme E2 variant 1.
     
  0.806
PISD
Phosphatidylserine decarboxylase proenzyme, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
   
 0.739
ENSACIP00000002899
Uncharacterized protein.
    
 
 0.725
ENSACIP00000011669
Mov10 RISC complex RNA helicase a.
    
 
 0.725
ENSACIP00000016003
Moloney leukemia virus 10b, tandem duplicate 1.
    
 
 0.725
ENSACIP00000030382
Ankyrin repeat, SAM and basic leucine zipper domain containing 1.
  
 0.717
PLD4
Phospholipase D family member 4.
     
 0.706
ENSACIP00000001060
Elongin C paralog a; Belongs to the SKP1 family.
    
 
 0.703
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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