Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ENSACIP00000004895NACHT domain-containing protein. (688 aa)    
Predicted Functional Partners:
ENSACIP00000028405
PYD and CARD domain containing.
   
 0.737
ENSACIP00000006310
CARD_2 domain-containing protein.
    
 0.673
ENSACIP00000011521
NIMA-related kinase 7.
    
 0.664
ENSACIP00000000408
Receptor-interacting serine-threonine kinase 2.
   
 0.658
ENSACIP00000011664
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone.
    
  0.638
ENSACIP00000005284
Receptor-interacting serine-threonine kinase 4.
    
  0.580
MLKL
Mixed lineage kinase domain like pseudokinase.
    
  0.579
ENSACIP00000027879
Protein kinase domain-containing protein.
    
  0.576
ENSACIP00000016746
CARD domain-containing protein.
   
 0.569
ENSACIP00000002771
Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2.
    
  0.566
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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