Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACIP00000004965SH2 domain-containing protein. (456 aa)    
Predicted Functional Partners:
ENSACIP00000027965
Aminoadipate aminotransferase.
      
 0.641
ENSACIP00000006680
Uncharacterized protein.
      
 0.637
ENSACIP00000020113
Bardet-Biedl syndrome 1.
      
 0.635
ENSACIP00000011667
V-crk avian sarcoma virus CT10 oncogene homolog-like.
    
 0.446
ENSACIP00000016508
Uncharacterized protein.
    
 0.446
CRK
CRK proto-oncogene, adaptor protein.
    
 0.446
ENSACIP00000027257
Tyrosine-protein kinase.
    
 0.418
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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