Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACIP00000004987Biogenesis of lysosomal organelles complex-1, subunit 5, muted. (157 aa)    
Predicted Functional Partners:
ENSACIP00000017499
Biogenesis of lysosomal organelles complex-1, subunit 2.
    
 0.996
ENSACIP00000019076
Biogenesis of lysosomal organelles complex-1, subunit 1.
   
 0.995
ENSACIP00000022152
Biogenesis of lysosome-related organelles complex 1 subunit 3; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). Belongs to the BLOC1S3 family.
    
 0.995
ENSACIP00000025582
Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...]
    
 0.995
ENSACIP00000020886
Biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino.
    
 0.985
ENSACIP00000017209
SNAP associated protein.
   
 0.981
ENSACIP00000020792
Dystrobrevin binding protein 1b.
    
 0.969
ENSACIP00000020800
Uncharacterized protein.
    
 0.969
ENSACIP00000006952
SWI5 homologous recombination repair protein.
    
 
 0.895
ENSACIP00000030209
HPS3 biogenesis of lysosomal organelles complex 2 subunit 1.
      
 0.856
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.