Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSACIP00000005115Pleckstrin homology domain containing, family N member 1. (683 aa)    
Predicted Functional Partners:
ENSACIP00000029703
Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family.
    
   0.821
ENSACIP00000011060
Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family.
    
 
 0.652
ENSACIP00000002753
Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
      
 0.627
ENSACIP00000022867
Anoctamin.
      
 0.623
ENSACIP00000021172
Elongator acetyltransferase complex subunit 2.
    
  0.577
ENSACIP00000005483
Glycine amidinotransferase (L-arginine:glycine amidinotransferase).
   
 0.556
ENSACIP00000006665
Fras1 related extracellular matrix 1b.
    
 0.555
ENSACIP00000018345
Fras1 related extracellular matrix 1a.
    
 0.555
ENSACIP00000003106
Fraser extracellular matrix complex subunit 1.
   
 0.554
ENSACIP00000010695
Sema domain-containing protein.
    
  0.552
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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