| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CMPK1 | ENSACIP00000002347 | ENSACIP00000028449 | ENSACIP00000002347 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. | 0.884 |
| CMPK1 | ENSACIP00000004566 | ENSACIP00000028449 | ENSACIP00000004566 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Nucleoside diphosphate kinase. | 0.902 |
| CMPK1 | ENSACIP00000005145 | ENSACIP00000028449 | ENSACIP00000005145 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Ectonucleoside triphosphate diphosphohydrolase 5b; Belongs to the GDA1/CD39 NTPase family. | 0.937 |
| CMPK1 | ENSACIP00000006590 | ENSACIP00000028449 | ENSACIP00000006590 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Ectonucleoside triphosphate diphosphohydrolase 4; Belongs to the GDA1/CD39 NTPase family. | 0.872 |
| CMPK1 | ENSACIP00000019449 | ENSACIP00000028449 | ENSACIP00000019449 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.517 |
| CMPK1 | ENSACIP00000027193 | ENSACIP00000028449 | ENSACIP00000027193 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Ectonucleoside triphosphate diphosphohydrolase 2b; Belongs to the GDA1/CD39 NTPase family. | 0.884 |
| CMPK1 | ENSACIP00000027390 | ENSACIP00000028449 | ENSACIP00000027390 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family. | 0.884 |
| CMPK1 | ENTPD7 | ENSACIP00000028449 | ENSACIP00000025953 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Ectonucleoside triphosphate diphosphohydrolase 7; Belongs to the GDA1/CD39 NTPase family. | 0.872 |
| CMPK1 | ITPA | ENSACIP00000028449 | ENSACIP00000017911 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | 0.823 |
| CMPK1 | NT5M | ENSACIP00000028449 | ENSACIP00000026555 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | 5',3'-nucleotidase, mitochondrial. | 0.873 |
| ENSACIP00000002347 | CMPK1 | ENSACIP00000002347 | ENSACIP00000028449 | Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | 0.884 |
| ENSACIP00000002347 | ENSACIP00000004566 | ENSACIP00000002347 | ENSACIP00000004566 | Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. | Nucleoside diphosphate kinase. | 0.872 |
| ENSACIP00000002347 | ENSACIP00000005145 | ENSACIP00000002347 | ENSACIP00000005145 | Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. | Ectonucleoside triphosphate diphosphohydrolase 5b; Belongs to the GDA1/CD39 NTPase family. | 0.916 |
| ENSACIP00000002347 | ENSACIP00000006590 | ENSACIP00000002347 | ENSACIP00000006590 | Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. | Ectonucleoside triphosphate diphosphohydrolase 4; Belongs to the GDA1/CD39 NTPase family. | 0.853 |
| ENSACIP00000002347 | ENSACIP00000019449 | ENSACIP00000002347 | ENSACIP00000019449 | Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.893 |
| ENSACIP00000002347 | ENSACIP00000027390 | ENSACIP00000002347 | ENSACIP00000027390 | Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. | Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family. | 0.865 |
| ENSACIP00000002347 | ENTPD7 | ENSACIP00000002347 | ENSACIP00000025953 | Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. | Ectonucleoside triphosphate diphosphohydrolase 7; Belongs to the GDA1/CD39 NTPase family. | 0.853 |
| ENSACIP00000002347 | ITPA | ENSACIP00000002347 | ENSACIP00000017911 | Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | 0.872 |
| ENSACIP00000002347 | NT5M | ENSACIP00000002347 | ENSACIP00000026555 | Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. | 5',3'-nucleotidase, mitochondrial. | 0.866 |
| ENSACIP00000004566 | CMPK1 | ENSACIP00000004566 | ENSACIP00000028449 | Nucleoside diphosphate kinase. | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | 0.902 |