Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSACIP00000005300Mitogen-activated protein kinase kinase kinase 7. (564 aa)    
Predicted Functional Partners:
ENSACIP00000005765
TGF-beta activated kinase 1/MAP3K7 binding protein 1.
  
 0.995
ENSACIP00000027317
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.995
ENSACIP00000015950
TGF-beta activated kinase 1 (MAP3K7) binding protein 3.
   
 0.993
ENSACIP00000026146
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.992
ENSACIP00000013226
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
 0.987
ENSACIP00000009916
Mitogen-activated protein kinase kinase 7.
   
 0.983
ENSACIP00000005798
Interleukin-1 receptor-associated kinase 1.
    
 0.981
ENSACIP00000022537
Component of inhibitor of nuclear factor kappa B kinase complex.
   
 0.975
ENSACIP00000023815
Inhibitor of nuclear factor kappa B kinase subunit beta.
   
 0.975
MAP2K6
Mitogen-activated protein kinase kinase 6.
    
 0.972
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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