Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
YY1YY1 transcription factor b. (370 aa)    
Predicted Functional Partners:
ENSACIP00000003437
Enhancer of zeste 2 polycomb repressive complex 2 subunit.
   
 0.952
EZH1
Enhancer of zeste 1 polycomb repressive complex 2 subunit.
   
 0.952
ENSACIP00000003920
Nuclear factor related to kappaB binding protein.
    
 0.951
ENSACIP00000003173
Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily.
    
 0.949
ENSACIP00000017439
INO80 complex subunit C.
    
 0.949
ENSACIP00000030379
Actin related protein 5; Belongs to the actin family.
    
 0.947
ENSACIP00000002455
INO80 complex ATPase subunit.
   
  0.945
ENSACIP00000028973
RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.
    
 0.945
ENSACIP00000031103
YY1 transcription factor.
  
  
 
0.935
ENSACIP00000008684
TCF3 (E2A) fusion partner.
    
 0.930
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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