Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACIP00000005342TOX high mobility group box family member 3. (602 aa)    
Predicted Functional Partners:
ENSACIP00000003173
Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily.
    
 0.742
ENSACIP00000030379
Actin related protein 5; Belongs to the actin family.
    
 0.736
ENSACIP00000017439
INO80 complex subunit C.
    
 0.724
ENSACIP00000012372
SPT16 homolog, facilitates chromatin remodeling subunit.
   
 0.722
ENSACIP00000016361
Actin-like 6A; Belongs to the actin family.
   
 0.704
ENSACIP00000012752
RNA polymerase I subunit E.
    
 0.690
ENSACIP00000028973
RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.
    
 0.681
ENSACIP00000012789
Beclin 1, autophagy related.
    
 0.673
ENSACIP00000008767
General transcription factor IIH, polypeptide 1.
    
 0.667
ENSACIP00000020735
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family.
    
 0.657
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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