Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1133 aa)    
Predicted Functional Partners:
ENSACIP00000005247
Uncharacterized protein.
    
 0.962
ENSACIP00000008414
Guanine nucleotide binding protein (G protein), alpha 11a (Gq class).
    
 0.948
ENSACIP00000022944
Guanine nucleotide binding protein (G protein), alpha 11b (Gq class).
    
 0.948
ENSACIP00000005214
Guanine nucleotide binding protein (G protein), alpha 14a.
    
 0.942
ENSACIP00000000133
Inositol 1,4,5-trisphosphate receptor, type 2.
    
 0.934
ENSACIP00000000960
Inositol 1,4,5-trisphosphate receptor, type 3.
    
 0.934
ENSACIP00000012022
Inositol 1,4,5-trisphosphate receptor, type 1b.
    
 0.934
ENSACIP00000028950
Inositol 1,4,5-trisphosphate receptor, type 1a.
    
 0.934
ENSACIP00000006716
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.
   
 0.924
ENSACIP00000003584
Uncharacterized protein.
   
 0.914
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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