Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ENSACIP00000005809Tripartite motif containing 16. (538 aa)    
Predicted Functional Partners:
ENSACIP00000017602
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
    
 0.944
ENSACIP00000012470
Ring-box 1, E3 ubiquitin protein ligase.
    
 0.933
ENSACIP00000015692
Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.
    
 0.933
ENSACIP00000003379
Cullin 1b; Belongs to the cullin family.
    
 0.882
ENSACIP00000004062
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase.
    
 0.878
ENSACIP00000004601
F-box protein 4.
    
 0.865
ENSACIP00000019059
F-box and WD repeat domain containing 11b.
   
 0.862
ENSACIP00000006062
CULLIN_2 domain-containing protein; Belongs to the cullin family.
    
 0.815
CUL3
Cullin 3; Belongs to the cullin family.
    
 0.815
ENSACIP00000009407
Nudix (nucleoside diphosphate linked moiety X)-type motif 12.
    
  0.809
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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