Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSACIP00000006004Adenosylhomocysteinase-like 1; Belongs to the adenosylhomocysteinase family. (482 aa)    
Predicted Functional Partners:
ENSACIP00000031415
Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family.
    
  0.961
ENSACIP00000015839
Cystathionase (cystathionine gamma-lyase), like.
  
 0.921
ENSACIP00000029556
Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 0.913
ENSACIP00000003211
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.912
ENSACIP00000004348
Glycine N-methyltransferase.
   
 
 0.903
ENSACIP00000010399
Zgc:172121; Involved in the regulation of homocysteine metabolism.
  
 
 0.894
ENSACIP00000003831
CBS domain-containing protein.
  
 0.887
ENSACIP00000021746
Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 0.887
ENSACIP00000019984
PALP domain-containing protein.
  
 
 0.873
ENSACIP00000010933
DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
     
 0.872
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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