Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
ENSACIP00000006012Fibroblast growth factor receptor 2. (653 aa)    
Predicted Functional Partners:
ENSACIP00000025216
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
    
 0.989
ENSACIP00000008191
Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]
    
 0.986
ENSACIP00000013776
Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]
    
 0.986
ENSACIP00000025824
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
    
 0.982
ENSACIP00000002947
Fibroblast growth factor 3; Belongs to the heparin-binding growth factors family.
    
 0.980
ENSACIP00000001983
Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.
    
 0.976
ENSACIP00000015365
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
    
 0.969
ENSACIP00000021987
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
    
 0.965
ENSACIP00000024918
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
    
 0.965
ENSACIP00000028095
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
    
 0.965
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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