Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SPNS2Sphingolipid transporter 2. (503 aa)    
Predicted Functional Partners:
ENSACIP00000004311
Sphingosine-1-phosphate lyase 1.
      
 0.855
ENSACIP00000020291
3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.785
ENSACIP00000012942
Sphingomyelin phosphodiesterase 2b, neutral membrane (neutral sphingomyelinase).
     
 0.781
ENSACIP00000016557
Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
     
 0.750
ENSACIP00000005799
Si:ch211-212g7.6.
    
 0.725
ENSACIP00000028627
acidPPc domain-containing protein.
    
 0.725
ENSACIP00000002753
Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
     
 0.721
ENSACIP00000015520
Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.
    
 0.709
SPHK1
Sphingosine kinase 1.
     
 0.701
ENSACIP00000008834
DAGKc domain-containing protein.
     
 0.701
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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