Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
APBA3Amyloid beta precursor protein binding family A member 3. (727 aa)    
Predicted Functional Partners:
ENSACIP00000025740
Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.
   
 0.931
CASK
Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.
   
 0.931
APP
Amyloid beta precursor protein.
   
 
 0.890
ENSACIP00000029517
Amyloid beta (A4) precursor protein b.
   
 
 0.890
ENSACIP00000018425
Membrane protein, palmitoylated 1; Belongs to the MAGUK family.
   
 0.817
ENSACIP00000001266
Membrane protein, palmitoylated 2b (MAGUK p55 subfamily member 2); Belongs to the MAGUK family.
    
 0.761
ENSACIP00000001504
Uncharacterized protein; Belongs to the MAGUK family.
    
 0.761
ENSACIP00000020322
Membrane protein, palmitoylated 6a (MAGUK p55 subfamily member 6); Belongs to the MAGUK family.
    
 0.761
ENSACIP00000025493
Uncharacterized protein; Belongs to the MAGUK family.
    
 0.761
ENSACIP00000006859
Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.
    
 0.746
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
Server load: low (14%) [HD]