Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACIP00000006404Empty spiracles homeobox 1. (233 aa)    
Predicted Functional Partners:
ENSACIP00000016788
Brain-specific homeobox.
   
  0.808
ENSACIP00000010933
DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
      
 0.774
ENSACIP00000024954
Drosha ribonuclease III.
     
  0.708
SLC4A7
Anion exchange protein.
      
 0.641
ENSACIP00000007991
LIM homeobox 5.
    
 0.611
ENSACIP00000011432
LIM homeobox 1b.
    
 0.611
ENSACIP00000013176
LIM homeobox 1a.
    
 0.611
ENSACIP00000023702
DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
    
   0.598
ENSACIP00000021127
ADAM metallopeptidase domain 15.
      
 0.591
ENSACIP00000027468
X-ray repair complementing defective repair in Chinese hamster cells 6.
    
   0.560
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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