Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
ENSACIP00000006484Adaptor related protein complex 5 subunit sigma 1. (202 aa)    
Predicted Functional Partners:
ENSACIP00000008766
Adaptor related protein complex 5 subunit mu 1; Belongs to the adaptor complexes medium subunit family.
    
 0.991
ENSACIP00000024899
SPG11 vesicle trafficking associated, spatacsin.
    
 
 0.967
ENSACIP00000010839
Adaptor related protein complex 5 subunit zeta 1.
    
 0.916
ENSACIP00000002914
Checkpoint kinase 2.
     
  0.859
ENSACIP00000004243
Checkpoint kinase 1; Belongs to the protein kinase superfamily.
     
  0.859
ENSACIP00000025087
Zinc finger, FYVE domain containing 26.
    
 
 0.837
ENSACIP00000016531
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 2; Belongs to the 14-3-3 family.
     
  0.812
ENSACIP00000030233
14_3_3 domain-containing protein; Belongs to the 14-3-3 family.
     
  0.812
ENSACIP00000028953
Zinc finger and BTB domain containing 3.
      
 0.771
ENSACIP00000005217
Zinc finger protein 367.
      
 0.764
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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