Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACIP00000006509Ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family. (147 aa)    
Predicted Functional Partners:
ENSACIP00000015436
Thyroid hormone receptor interactor 12.
   
 0.954
ENSACIP00000016154
Ubiquitin-conjugating enzyme E2 variant 1.
   
 0.951
ENSACIP00000004126
Ribosomal protein S27a.
   
 0.936
ENSACIP00000014946
FA complementation group L.
   
 0.919
ENSACIP00000004626
Ubiquitin-conjugating enzyme E2D 1b.
    
  0.912
ENSACIP00000008627
Ubiquitin-conjugating enzyme E2D 1a; Belongs to the ubiquitin-conjugating enzyme family.
    
  0.912
ENSACIP00000010389
Uncharacterized protein.
   
 0.907
ENSACIP00000012470
Ring-box 1, E3 ubiquitin protein ligase.
   
 0.902
ENSACIP00000026009
APC11 anaphase promoting complex subunit 11 homolog (yeast).
    
 0.902
ENSACIP00000009054
STIP1 homology and U-Box containing protein 1.
    
 0.897
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
Server load: low (10%) [HD]