Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACIP00000006567Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (60 aa)    
Predicted Functional Partners:
ENSACIP00000011696
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
    
 
 0.636
ENSACIP00000031474
Antioxidant 1 copper chaperone.
   
  
 0.523
ENSACIP00000025647
Solute carrier family 30 member 4.
   
  
 0.497
ENSACIP00000002771
Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2.
    
 
 0.480
ENSACIP00000003502
Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1.
    
 
 0.480
ENSACIP00000018150
Heat shock protein 90, alpha (cytosolic), class B member 1.
    
 
 0.480
ENSACIP00000024491
Heat shock protein 90, beta (grp94), member 1.
    
 
 0.480
ENSACIP00000012007
Uncharacterized protein.
      
 0.476
ENSACIP00000015187
Solute carrier family 30 member 1a.
      
 0.476
ENSACIP00000003466
VRK serine/threonine kinase 3.
      
 0.468
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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