Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACIP00000006582TM2 domain containing 3. (206 aa)    
Predicted Functional Partners:
ENSACIP00000013465
NHL repeat containing 2.
      
 0.843
ENSACIP00000029419
Phosphatidylinositol glycan anchor biosynthesis, class A.
     
 0.822
ENSACIP00000026143
Mitochondrial ribosomal protein S18C.
      
 0.804
ENSACIP00000002294
Phosphatidylinositol glycan anchor biosynthesis, class H.
     
 0.787
ENSACIP00000014169
Phosphatidylinositol glycan anchor biosynthesis, class L.
     
 0.787
ENSACIP00000023376
Phosphatidylinositol N-acetylglucosaminyltransferase subunit P; Part of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.
   
 
 0.782
ENSACIP00000015359
Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family.
   
 
  0.779
ENSACIP00000025700
CDP-diacylglycerol--inositol 3-phosphatidyltransferase.
     
  0.768
ENSACIP00000000541
Signal peptidase complex subunit 1.
   
   0.747
ENSACIP00000015229
Phosphatidylinositol-glycan biosynthesis class W protein; Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.
     
 0.729
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
Server load: low (22%) [HD]