Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACIP00000006591Ig-like domain-containing protein; Belongs to the MHC class I family. (267 aa)    
Predicted Functional Partners:
ENSACIP00000004818
CD8a molecule.
    
 0.910
ENSACIP00000008276
TAP binding protein (tapasin), tandem duplicate 2.
   
 0.894
ENSACIP00000009624
Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
   
 0.888
ENSACIP00000009709
Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
   
 0.888
ENSACIP00000015699
TAP binding protein like.
  
 
 0.886
ENSACIP00000022141
Replication protein A2.
   
 0.863
ENSACIP00000010291
Calreticulin.
    
 0.841
ENSACIP00000010879
Calreticulin.
    
 0.841
ENSACIP00000015482
Protein disulfide-isomerase.
    
  0.830
ENSACIP00000009163
Protein disulfide-isomerase.
    
  0.807
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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