Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSACIP00000006595Helicase-like transcription factor. (925 aa)    
Predicted Functional Partners:
ENSACIP00000007861
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 0.996
ENSACIP00000026681
RAD18 E3 ubiquitin protein ligase.
   
 0.994
ENSACIP00000022928
Ubiquitin-conjugating enzyme E2Nb; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.991
ENSACIP00000023760
Ubiquitin-conjugating enzyme E2 variant 2.
    
 0.974
ENSACIP00000002311
Protein S100; Belongs to the S-100 family.
    
 
 0.945
ENSACIP00000005717
DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]
  
 
 0.944
ENSACIP00000001609
UBIQUITIN_CONJUGAT_2 domain-containing protein.
    
 0.942
ENSACIP00000001450
Chromodomain helicase DNA binding protein 1-like.
  
 
0.933
ENSACIP00000000966
MUS81 structure-specific endonuclease subunit.
   
 0.932
ENSACIP00000006898
ERCC4 domain-containing protein.
  
 0.925
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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