Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSACIP00000006883Membrane associated guanylate kinase, WW and PDZ domain containing 2b. (571 aa)    
Predicted Functional Partners:
ENSACIP00000025985
Catenin (cadherin-associated protein), beta 1.
    
 0.958
ENSACIP00000004128
Phosphatase and tensin homolog A; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
    
 0.908
ENSACIP00000010421
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
    
 0.908
ENSACIP00000015616
Transmembrane phosphatase with tensin homology.
    
 0.908
ENSACIP00000004262
Immunoglobulin superfamily, member 5a.
   
 0.885
ENSACIP00000002372
Rap guanine nucleotide exchange factor (GEF) 2.
    
 0.882
ENSACIP00000018654
Rap guanine nucleotide exchange factor (GEF) 6.
    
 0.882
ENSACIP00000012061
Uncharacterized protein.
     
 0.820
ENSACIP00000014707
Membrane associated guanylate kinase, WW and PDZ domain containing 3b.
   
 
 0.815
ENSACIP00000018854
Uncharacterized protein.
   
 
 0.815
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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