Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACIP00000007007TIR domain-containing protein. (946 aa)    
Predicted Functional Partners:
ENSACIP00000026146
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
    
 0.829
ENSACIP00000027939
Toll-interleukin 1 receptor (TIR) domain containing adaptor protein.
    
 0.676
ENSACIP00000001574
Uncharacterized protein.
    
  0.617
ENSACIP00000024340
Uncharacterized protein.
    
  0.617
ENSACIP00000007237
Transmembrane p24 trafficking protein 7.
    
 0.581
ENSACIP00000027164
Transmembrane p24 trafficking protein 3.
    
 0.581
ENSACIP00000027503
Toll-like receptor adaptor molecule 1.
    
 0.581
ENSACIP00000028245
Heat shock protein 9; Belongs to the heat shock protein 70 family.
    
  0.570
ENSACIP00000024491
Heat shock protein 90, beta (grp94), member 1.
    
 0.560
ENSACIP00000012252
Uncharacterized protein; Belongs to the TCP-1 chaperonin family.
    
  0.545
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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