STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSACIP00000017107Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (57 aa)    
Predicted Functional Partners:
ENSACIP00000004062
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase.
   
 0.984
ENSACIP00000017602
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
    
 0.975
ENSACIP00000003379
Cullin 1b; Belongs to the cullin family.
    
 0.949
ENSACIP00000012470
Ring-box 1, E3 ubiquitin protein ligase.
   
 0.937
ENSACIP00000024245
Cyclin A2; Belongs to the cyclin family.
   
 0.929
ENSACIP00000030445
Cyclin A1; Belongs to the cyclin family.
   
 0.929
ENSACIP00000002568
Cyclin-dependent kinase 4.
   
 0.878
ENSACIP00000002579
Protein kinase domain-containing protein.
   
 0.878
ENSACIP00000003392
Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily.
   
 0.878
ENSACIP00000025519
Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.
   
 0.878
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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