STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSACIP00000017240Nuclear receptor subfamily 1, group D, member 4a. (578 aa)    
Predicted Functional Partners:
ENSACIP00000031671
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 0.895
ENSACIP00000000142
Nuclear receptor subfamily 1, group H, member 4.
   
0.881
ENSACIP00000014054
Uncharacterized protein.
    
 0.881
ENSACIP00000018888
Nuclear receptor subfamily 1, group H, member 5.
   
0.881
ENSACIP00000025884
Nuclear receptor corepressor 2.
    
 0.881
NR1H2
Nuclear receptor subfamily 1 group H member 2.
   
0.881
ENSACIP00000014136
GPS2_interact domain-containing protein.
    
 0.869
ENSACIP00000020010
Vitamin D receptor b.
   
0.842
ENSACIP00000021289
Uncharacterized protein.
   
0.842
ENSACIP00000002282
Peroxisome proliferator-activated receptor delta b.
    
0.824
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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