STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A3Q0KDM0GTP cyclohydrolase I. (459 aa)    
Predicted Functional Partners:
Smp_072080
Pyruvoyl tetrahydrobiopterin synthase, putative.
  
 
 0.977
Smp_094820
Vta1 domain-containing protein.
   
   0.939
A0A3Q0KCF9
Coronin; Belongs to the WD repeat coronin family.
    
 0.911
A0A3Q0KRC4
Folylpolyglutamate synthase.
  
  
 0.789
A0A5K4EUG5
Folylpolyglutamate synthase.
  
  
 0.789
A0A3Q0KMZ1
Putative glutamyl-tRNA synthetase, cytoplasmic (Glutamate--tRNA ligase) (Glurs).
  
  
 0.785
A0A3Q0KGU1
Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
 
 0.774
A0A3Q0KD50
Reticulon-like protein.
    
   0.764
Smp_058240
Reticulon-like protein.
    
   0.764
Smp_082620
CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.
  
  
 0.762
Your Current Organism:
Schistosoma mansoni
NCBI taxonomy Id: 6183
Other names: S. mansoni
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