STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A3Q0KVH5ATP-dependent RNA helicase, putative; Belongs to the MAGUK family. (1165 aa)    
Predicted Functional Partners:
A0A5K4FBD9
Uncharacterized protein.
    
 0.701
A0A5K4FCQ9
Uncharacterized protein.
    
 0.701
A0A5K4F0S6
HMG-CoA synthase.
   
 
 0.661
A0A3Q0KQJ8
Putative sh3 and multiple ankyrin repeat domains protein 1,2 (Shank1,2).
    
 0.633
Smp_073570
Putative DNA-directed rna polymerase subunit rpb6.
  
  
 0.628
Smp_055600
Lin-7-like proteins.
    
 0.572
Smp_030180
Ubiquitin-related modifier 1 homolog; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3/UBA4 homolog. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxid [...]
    
 0.572
A0A5K4EMU0
Dynamin-associated protein, putative.
    
  0.541
Smp_063830
GMP synthetase (Glutamine-hydrolysing).
  
 
 0.540
A0A3Q0KNT8
Amyloid beta A4 protein related.
    
 0.527
Your Current Organism:
Schistosoma mansoni
NCBI taxonomy Id: 6183
Other names: S. mansoni
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.