STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A5K4EJB5Adenosylhomocysteinase. (159 aa)    
Predicted Functional Partners:
Smp_125070.1
Cysteine synthase, putative.
  
 0.846
Smp_210320
Hcy-binding domain-containing protein.
  
 
 0.832
A0A3Q0KBJ2
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
  
 
 0.762
A0A3Q0KNY0
Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
     
 0.688
A0A5K4FB58
Uncharacterized protein.
    
 0.584
A0A5K4FC10
Uncharacterized protein.
    
 0.584
Smp_012930
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
   
  
 0.574
Smp_073500.2
Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
   
  
 0.572
Smp_033670.5
ATP synthase gamma subunit, putative; ATP synthase subunit gamma.
   
  
 0.563
A0A3Q0KIF2
Putative cystathionine beta-lyase.
  
 0.553
Your Current Organism:
Schistosoma mansoni
NCBI taxonomy Id: 6183
Other names: S. mansoni
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.