STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A5K4EUV4Ap endonuclease, putative. (72 aa)    
Predicted Functional Partners:
NTH1
Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family.
  
 0.784
A0A5K4F9K2
Uncharacterized protein.
   
 0.774
A0A3Q0KBF4
Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.
    
 0.729
A0A3Q0KHR6
Putative 8-oxoguanine DNA glycosylase.
  
 0.715
A0A5K4F0G3
Uncharacterized protein.
   
 0.700
Smp_068420
Small nuclear ribonucleoprotein Sm D3.
   
 0.671
Smp_060910
Putative small nuclear ribonucleoprotein f (Snrnp-f).
   
 0.636
Smp_075560
Small nuclear ribonucleoprotein Sm D2.
   
 0.629
A0A3Q0KPH0
Putative g/t mismatch-specific thymine DNA glycosylase.
  
 
 0.625
A0A3Q0KR09
Enkurin domain-containing protein.
    
 0.625
Your Current Organism:
Schistosoma mansoni
NCBI taxonomy Id: 6183
Other names: S. mansoni
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.